<link rel="stylesheet" href="https://studioyszimg.yxj.org.cn/css/video-js.min.css?v=1"><link rel="stylesheet" href="https://studioyszimg.yxj.org.cn/article/css/base.css?v=5"><link rel="stylesheet" href="https://studioyszimg.yxj.org.cn/article/css/index.css?v=35"><link rel="stylesheet" href="https://ysz-web.yxj.org.cn/live/dist/static/base/index.css?ysz_v=2.0"><script src="https://studioyszimg.yxj.org.cn/js/dsbridge.js?v=13" type="text/javascript"></script><script src="https://ysz-web.yxj.org.cn/dsBridge/main.js?v=26" type="text/javascript"></script><script src="https://ysz-web.yxj.org.cn/live/dist/static/base/fun.js?ysz_v=3" type="text/javascript"></script><script src="https://ysz-web.yxj.org.cn/live/dist/static/js/nativeToWeb.js?v=1" type="text/javascript"></script><div id="ysz-header" style="margin:0;overflow:hidden;"><h1 style="font-size:24px;line-height:1.8;color:#333333;word-wrap:break-word;">一举两得,打疫苗居然还能防卒中</h1><h2 style="font-size:16px;color:#999999;word-wrap:break-word;"><em style="font-style:normal;margin-right:10px;color:#7f7f7f;display:inline-block;">2022-02-25</em><em style="font-style:normal;margin-right:10px;color:#7f7f7f;display:inline-block;">原创:医学界</em></h2></div><p class="brief">接种流感疫苗的好处可能远远超过预期</p><p style="text-align: justify;"><span class="ysz-ueditor-content" style="font-size: 16px; line-height: 28px; color: rgb(0, 0, 0);">根据《全国第三次死因回顾抽样调查报告》,脑血管病目前已跃升为国民死亡原因之首,其中脑卒中是单病种致残率最高的疾病<sup>1</sup>。</span></p><p><br/></p><p style="text-align: justify;"><span class="ysz-ueditor-content" style="font-size: 16px; line-height: 28px; color: rgb(0, 0, 0);">很多人都不知道的是,流感也是脑卒中的高危因素之一。一场看似普通的流感,可能就是脑卒中的导火索。因此,预防流感,也等于同时预防了脑卒中。</span></p><p><br/></p><p style="text-align: justify;"><span class="ysz-ueditor-title-one" style="font-size: 16px; line-height: 28px; font-weight: bold; color: rgb(215, 0, 15); text-align: left;">流感病毒感染或许是脑卒中的导火索,</span></p><p style="text-align: justify;"><span class="ysz-ueditor-title-one" style="font-size: 16px; line-height: 28px; font-weight: bold; color: rgb(215, 0, 15); text-align: left;">还可能加重脑卒中结局</span></p><p><br/></p><p style="text-align: justify;"><span class="ysz-ueditor-content" style="font-size: 16px; line-height: 28px; color: rgb(0, 0, 0);">流感病毒感染可引发脑卒中。苏格兰一项自身对照病例系列研究,纳入2004年1月1日-2014年12月31日实验室确诊细菌或病毒感染后的762例新发脑卒中和1227例新发心肌梗死患者,旨在量化实验室确诊的呼吸道细菌或病毒感染与新发脑卒中和心肌梗死之间的相关性。</span></p><p><br/></p><p style="text-align: justify;"><span class="ysz-ueditor-content" style="font-size: 16px; line-height: 28px; color: rgb(0, 0, 0);">结果显示:流感感染后1-3天内脑卒中首次发作风险增加7.82倍(95%CI:1.07-56.9,P=0.042)<sup>2</sup>。</span></p><p><br/></p><p style="text-align: center;"><span style="line-height: 28px; font-size: 14px; color: rgb(136, 136, 136);">流感病毒感染增加脑卒中首次发作风险<sup>2</sup></span></p><p style="text-align: center;"><img class="rich_pages wxw-img" src="https://studioyszimg.yxj.org.cn/AC14B006017F30B7F03D48E565545383.jpg" alt="图片" style="margin: 0px; padding: 0px; outline: 0px; vertical-align: bottom; width: 661px; box-sizing: border-box ; overflow-wrap: break-word ; visibility: visible ;"/></p><p><br/></p><p style="text-align: justify;"><span class="ysz-ueditor-content" style="font-size: 16px; line-height: 28px; color: rgb(0, 0, 0);">近期美国一项研究显示,流感样疾病住院事件与缺血性卒中发生几率增加显著相关。该研究对2012-2014年纽约全州规划和研究合作系统进行病例交叉分析,旨在估计流感样疾病后缺血性卒中和心肌梗死的几率。结果显示:前15天因流感样疾病住院使缺血性卒中的发生几率增加39%(OR=1.39;95% CI:1.09-1.77;P&lt;0.05)。前一年因流感样疾病住院使缺血性卒中的发生几率增加69%(OR=1.69;95%CI:1.56-1.83;P&lt;0.05)<sup>3</sup>。</span></p><p><br/></p><p style="text-align: justify;"><span class="ysz-ueditor-content" style="font-size: 16px; line-height: 28px; color: rgb(0, 0, 0);">流感还可能加重脑卒中结局。一项基础研究用HIN1病毒感染小鼠,并阻塞大脑中动脉诱发缺血性脑卒中,通过组织学测定梗死体积和脑内出血,旨在评估H1N1感染对小鼠缺血性脑卒中结局的影响。结果显示:H1N1感染后小鼠脑卒中的梗死体积增加<sup>4</sup>。</span></p><p><br/></p><p style="text-align: justify;"><span class="ysz-ueditor-title-one" style="font-size: 16px; line-height: 28px; font-weight: bold; color: rgb(215, 0, 15); text-align: left;">接种流感疫苗的好处可能远远超过预期</span></p><p><br/></p><p style="text-align: justify;"><span class="ysz-ueditor-content" style="font-size: 16px; line-height: 28px; color: rgb(0, 0, 0);">接种流感疫苗能降低新发脑卒中、再发脑卒中、任何脑卒中发生风险。一项荟萃分析纳入11项调查流感疫苗接种对随后脑卒中风险影响的研究,旨在确定接种流感疫苗是否能预防脑卒中。结果显示:接种流感疫苗显著降低脑卒中发生风险(OR=0.82;95% CI:0.75-0.91;P&lt;0.001)。其中4项研究显示接种流感疫苗降低新发脑卒中风险(OR=0.81;95%CI:0.78-0.85),3项研究显示接种流感疫苗降低再发脑卒中风险(OR=0.75;95%CI:0.70-1.01),其中7项研究显示接种流感疫苗降低任何脑卒中发生风险(OR=0.73;95%CI:0.59-0.90)<sup>5</sup>。</span></p><p><br/></p><p style="text-align: center;"><span style="line-height: 28px; font-size: 14px; color: rgb(136, 136, 136);">接种流感疫苗降低脑卒中发生风险<sup>5</sup></span></p><p style="text-align: center;"><img class="rich_pages wxw-img" src="https://studioyszimg.yxj.org.cn/AC14B006017F30B7F12BC3126944DFCD.jpg" alt="图片" style="margin: 0px; padding: 0px; outline: 0px; vertical-align: bottom; box-sizing: border-box ; overflow-wrap: break-word ; width: 563px ; visibility: visible ;"/></p><p><br/></p><p style="text-align: justify;"><span class="ysz-ueditor-content" style="font-size: 16px; line-height: 28px; color: rgb(0, 0, 0);">接种流感疫苗能降低缺血性脑卒中住院风险,且缺血性脑卒中住院风险随流感疫苗接种数量增加而显著降低。台湾一项基于人群的病例对照研究,纳入2006-2009年流感季的520例65岁以上缺血性脑卒中住院患者和2600例匹配对照,旨在研究流感疫苗接种对缺血性脑卒中住院风险的影响。结果显示:接种流感疫苗降低老年人缺血性脑卒中住院风险,且每年接种会提供更多保护<sup>6</sup>。</span></p><p><br/></p><p style="text-align: center;"><span style="line-height: 28px; font-size: 14px; color: rgb(136, 136, 136);">接种流感疫苗降低缺血性脑卒中住院风险<sup>6</sup></span></p><p style="text-align: center;"><img class="rich_pages wxw-img" src="https://studioyszimg.yxj.org.cn/AC14B006017F30B7F2468F635DC03E19.jpg" alt="图片" style="margin: 0px; padding: 0px; outline: 0px; vertical-align: bottom; box-sizing: border-box ; overflow-wrap: break-word ; width: 562px ; visibility: visible ;"/></p><p><br/></p><p style="text-align: justify;"><span class="ysz-ueditor-content" style="font-size: 16px; line-height: 28px; color: rgb(0, 0, 0);">接种流感疫苗还能显著降低脑卒中死亡风险。一项研究纳入102698例65岁以上老年人,分为接种流感疫苗组(n=35637)和未接种流感疫苗组(n=67061),旨在研究流感疫苗是否有效降低主要原因死亡风险。结果显示:接种流感疫苗可显著降低全因死亡风险(HR=0.56;95%CI:0.52-0.60,P&lt;0.05),其中脑卒中的死亡风险降低了65%(HR=0.35;95%CI:0.27-0.45,P&lt;0.05)<sup>7</sup>。</span></p><p><br/></p><p style="text-align: center;"><span style="line-height: 28px; font-size: 14px; color: rgb(136, 136, 136);">接种流感疫苗降低脑卒中死亡风险<sup>7</sup></span></p><p style="text-align: center;"><img class="rich_pages wxw-img" src="https://studioyszimg.yxj.org.cn/AC14B006017F30B7F33C873B1944268F.jpg" alt="图片" style="margin: 0px; padding: 0px; outline: 0px; vertical-align: bottom; width: 661px; box-sizing: border-box ; overflow-wrap: break-word ; visibility: visible ;"/></p><p><br/></p><p style="text-align: justify;"><span class="ysz-ueditor-title-one" style="font-size: 16px; line-height: 28px; font-weight: bold; color: rgb(215, 0, 15); text-align: left;">指南推荐:每年接种流感疫苗</span></p><p style="text-align: justify;"><span class="ysz-ueditor-title-one" style="font-size: 16px; line-height: 28px; font-weight: bold; color: rgb(215, 0, 15); text-align: left;">可有效降低脑卒中患者的脑卒中风险</span></p><p><br/></p><p style="text-align: center;"><img class="rich_pages wxw-img" src="https://studioyszimg.yxj.org.cn/AC14B006017F30B7F435020746A1F149.jpg" alt="图片" style="margin: 0px; padding: 0px; outline: 0px; vertical-align: bottom; width: 661px; box-sizing: border-box ; overflow-wrap: break-word ; visibility: visible ;"/></p><p><br/></p><p style="text-align: justify;"><span class="ysz-ueditor-content" style="font-size: 16px; line-height: 28px; color: rgb(0, 0, 0);">综上所述,接种流感疫苗不仅能预防流感,还能有效降低脑卒中发生风险,真是一举两得!那今年的流感疫苗,您打了吗?若还没打,请尽快前往附近的社区卫生服务中心预约和接种吧!</span></p><div class="footer"><div class="item"><p class="ysz-ueditor-references-label" >参考文献 <span>共8篇<i></i></span></p><div class="ysz-ueditor-references-content textLine2" lang="en"><p style="text-align: justify;"><span class="ysz-ueditor-content" style="font-size: 16px; line-height: 28px; color: rgb(0, 0, 0);">[1]<span class="appskip" data-appskip="yxjysz" data-appskipobj="{&quot;type&quot;:18,&quot;id&quot;:0,&quot;title&quot;:&quot;&quot;,&quot;url&quot;:&quot;https://cn.bing.com/search?q=%E4%B8%AD%E5%8D%8E%E4%BA%BA%E6%B0%91%E5%85%B1%E5%92%8C%E5%9B%BD%E5%9B%BD%E5%AE%B6%E5%8D%AB%E7%94%9F%E5%81%A5%E5%BA%B7%E5%A7%94%E5%91%98%E4%BC%9A.+%E4%B8%AD%E5%9B%BD%E8%84%91%E5%8D%92%E4%B8%AD%E9%98%B2%E6%B2%BB%E6%8C%87%E5%AF%BC%E8%A7%84%E8%8C%83%EF%BC%882021%E5%B9%B4%E7%89%88%EF%BC%89.&amp;form=QBLH&amp;sp=-1&amp;pq=%E4%B8%AD%E5%8D%8E%E4%BA%BA%E6%B0%91%E5%85%B1%E5%92%8C%E5%9B%BD%E5%9B%BD%E5%AE%B6%E5%8D%AB%E7%94%9F%E5%81%A5%E5%BA%B7%E5%A7%94%E5%91%98%E4%BC%9A.+%E4%B8%AD%E5%9B%BD%E8%84%91%E5%8D%92%E4%B8%AD%E9%98%B2%E6%B2%BB%E6%8C%87%E5%AF%BC%E8%A7%84%E8%8C%83%EF%BC%882021%E5%B9%B4%E7%89%88%EF%BC%89.&amp;sc=0-38&amp;qs=n&amp;sk=&amp;cvid=38887451125A46E5B2E09B243AAC1918&quot;}">中华人民共和国国家卫生健康委员会. 中国脑卒中防治指导规范(2021年版).</span></span></p><p><section><section><section><section><section><section style="text-align: justify;"><span class="ysz-ueditor-content" style="font-size: 16px; 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