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Mostpatients whoundergosurgicalproceduresexperience acutepostoperativepain, butev-idence suggests that less than half report adequate postoperative pain relief. Many preoperative, intra-operative, and postoperative interventions and management strategies are available for reducing andmanaging postoperative pain. The American Pain Society, with input from the American Society of Anes-thesiologists, commissioned an interdisciplinary expert panel to develop a clinical practice guideline topromote evidence-based, effective, and safer postoperative pain management in children and adults.The guideline was subsequently approved by the American Society for Regional Anesthesia. As part ofthe guideline development process, a systematic review was commissioned on various aspects relatedto various interventions and management strategies for postoperative pain. After a review of the evi-dence, the expert panel formulated recommendations that addressed various aspects of postoperativepain management, including preoperative education, perioperative pain management planning, use ofdifferent pharmacological and nonpharmacological modalities, organizational policies, and transitiontooutpatientcare.Therecommendationsarebasedontheunderlyingpremisethatoptimalmanagementbegins in the preoperative period with an assessment of the patient and development of a plan of caretailored to the individual and the surgical procedure involved. The panel found that evidence supportsthe use of multimodal regimens in many situations, although the exact components of effective multi-modal care will vary depending on the patient, setting, and surgical procedure. Although these guide-lines are based on a systematic review of the evidence on management of postoperative pain, thepanel identified numerous research gaps. Of 32 recommendations, 4 were assessed as being supportedby high-quality evidence, and 11 (in the areas of patient education and perioperative planning, patientassessment, organizational structures and policies, and transitioning to outpatient care) were made onthe basis of low-quality evidence.
Perspective:This guideline, on the basis of a systematic review of the evidence on postoperative painmanagement, provides recommendations developed by a multidisciplinary expert panel. Safe and effec-tive postoperative pain management should be on the basis of a plan of care tailored to the individual andthe surgical procedure involved, and multimodal regimens are recommended in many situations.

