Rhabdomyolysis is a clinical condition characterized by destruction of skeletal muscle with release of intracellular contents into the bloodstream. Intracellular contents released include electrolytes, enzymes, and myoglobin, resulting in systemic complications. Muscle necrosis is the common factor for traumatic and non-traumatic rhabdomyolysis. The systemic impact of rhabdomyolysis ranges from asymptomatic elevations in bloodstream muscle enzymes to life-threatening acute kidney injury and electrolyte abnormalities. The purpose of this clinical consensus statement is to review the present-day diagnosis, management, and prognosis of patients who develop rhabdomyolysis.

横纹肌溶解是一种以骨骼肌破坏伴细胞内内容物释放到血液中为特征的临床疾病。释放的细胞内内容物包括电解质、酶和肌红蛋白，导致全身并发症。肌肉坏死是创伤性和非创伤性横纹肌溶解症的常见因素。横纹肌溶解的全身影响范围从无症状的血流肌酶升高至危及生命的急性肾损伤和电解质异常。本临床共识声明的目的是审查发生横纹肌溶解症患者的当前诊断、管理和预后。