Improving Global Outcomes (KDIGO) 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease (CKD) is an update to the KDIGO 2012 guideline on the topic. The aim is to assist clinicians caring for people with CKD, both adults and children. People receiving dialysis and kidney transplant recipients are not the focus of this guideline. The scope includes chapters dedicated to the evaluation of CKD, risk assessment in people with CKD, management to delay CKD progression and manage its complications, medical management and drug stewardship in CKD, and optimal models of CKD care. In addition, this guideline includes a comprehensive introduction from the guideline Co-Chairs, a patient foreword, a discussion of special population considerations, a presentation of the relative and absolute risks associated with specific outcomes from the CKD Prognosis Consortium (CKDPC), and an extensive section dedicated to research recommendations based on the current gaps in evidence. The goal of the guideline is to generate a useful resource for clinicians and patients by providing actionable recommendations based on a rigorous formal evidence review, practice points that serve to direct clinical care or activities for which a systematic review was not conducted, and useful infographics. The guideline targets a broad audience of healthcare providers involved in the care of people with CKD as well as people with CKD themselves while being mindful of implications for policy and payment. Development of this guideline update followed an explicit process of evidence review and appraisal. Treatment approaches and guideline recommendations are based on systematic reviews of relevant studies, and appraisal of the certainty of the evidence and the strength of recommendations followed the “Grading of Recommendations Assessment, Development, and Evaluation” (GRADE) approach. Limitations of the evidence are discussed, with areas of future research also presented.

改善全球结局(KDIGO)2024临床实践指南慢性肾病(CKD)的评价和管理是KDIGO的更新2012年关于该主题的指南。目的是帮助护理CKD患者的临床医生，包括成人和儿童。接受透析的人和肾移植受者不是重点本指导原则。该范围包括专门针对CKD评价、风险评估的章节CKD患者，管理以延缓CKD进展并管理其并发症，医学CKD的管理和药物管理，以及CKD护理的最佳模式。此外，本指南包括指南联合主席、患者的全面介绍前言，对特殊人群考虑的讨论，亲属和CKD预后联盟(CKDPC)特定结局相关的绝对风险，以及基于当前差距专门针对研究建议的广泛章节作为证据。该指南的目标是通过以下方式为临床医生和患者生成有用的资源基于严格的正式证据审查、实践提供可操作的建议用于指导未进行系统性综述的临床护理或活动的要点，以及有用的信息图。该指南针对广泛的医疗保健提供者受众参与CKD患者以及CKD患者本身的护理注意对政策和付款的影响。随后制定了本指导原则更新证据审查和评估的明确过程。治疗方法和指南建议是基于相关研究的系统综述和确定性评估的证据和建议的强度遵循“建议评估、开发和评价分级”(GRADE)方法。讨论了证据的局限性，还介绍了未来研究的领域。