The 2019 ESC (European Society of Cardiology) Guidelines for the diagnosis and management of chronic coronary syndromes introduced the term chronic coronary syndromes (CCS)  ESC Guidelines are based on analyses of published evidence, chiefly on clinical trials and meta-analyses of trials, but potentially including other types of studies. Evidence tables summarizing key information from relevant studies are generated early in the guideline development process to facilitate the formulation of recommendations, to enhance comprehension of recommendations after publication, and reinforce transparency in the guideline development process. The tables are pub lished in their own section of the ESC Guidelines and are specifically related to the recommendation tables. to describe the clinical presentations of coronary artery disease (CAD) during stable periods, particularly those preceding or following an acute coronary syndrome (ACS). CAD was defined as the pathological process characterized by atherosclerotic plaque accumulation in the epicardial arteries, whether obstructive or non-obstructive. Based on expanded pathophysiological concepts, a new, more comprehensive definition of CCS is introduced: 

 ‘CCS are a range of clinical presentations or syndromes that arise due to structural and/or functional alterations related to chronic diseases of the coronary arteries and/or microcircula tion. These alterations can lead to transient, reversible, myocar dial demand vs. blood supply mismatch resulting in hypoperfusion (ischaemia), usually (but not always) provoked by exertion, emotion or other stress, and may manifest as angina, other chest discomfort, or dyspnoea, or be asymptomatic. Although stable for long periods, chronic coronary diseases are frequently progressive and may destabilize at any moment with the development of an ACS.’ 

Of note, ‘disease’ refers to the underlying coronary pathology, and ‘syn drome’ refers to the clinical presentation.

2019年ESC（欧洲心脏病学会）慢性冠状动脉综合征诊断和管理指南引入了慢性冠状动脉综合征（CCS）这一术语，ESC指南基于对已发表证据的分析，主要是临床试验和试验荟萃分析，但可能包括其他类型的研究。在指南制定过程的早期生成总结相关研究关键信息的证据表，以促进建议的制定，在发布后增强对建议的理解，并加强指南制定过程的透明度。这些表格在ESC指南的单独章节中公布，并与推荐表格特别相关。描述冠状动脉疾病（CAD）在稳定期的临床表现，特别是急性冠状动脉综合征（ACS）之前或之后的临床表现。CAD被定义为以动脉粥样硬化斑块积聚在心外膜动脉为特征的病理过程，无论是阻塞性还是非阻塞性。基于病理生理学概念的扩展，本文引入了一个新的、更全面的CCS定义：

CCS是由于冠状动脉和/或微循环慢性疾病相关的结构和/或功能改变而引起的一系列临床表现或综合征。这些改变可导致短暂的，可逆的，心肌需求与血液供应不匹配，导致灌注不足（缺血），通常（但不总是）由劳累，情绪或其他压力引起，并可能表现为心绞痛，其他胸部不适，或呼吸困难，或无症状。虽然长期稳定，但慢性冠状动脉疾病往往是进行性的，并可能随时随着ACS的发展而不稳定。

值得注意的是，“疾病”是指潜在的冠状动脉病理，“综合征”是指临床表现。