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ESPGHAN:儿童嗜酸性粒细胞性食管炎的诊断和管理指南(2024更新版)

制定者:
欧洲儿科胃肠病学、肝病学和营养协会(ESPGHAN,European Society for Paediatric Gastroenterology

2024年8月6日

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中英对照

Question: After a few years of difficulty swallowing solids and feeling like food was getting stuck, a 13-year-old boy in my practice with peanut allergy and asthma was recently diagnosed with eosinophilic esophagitis (EoE). What is EoE and how is it diagnosed and managed?

Answer: Eosinophilic esophagitis is an immune-mediated disease resulting in inflammation of the esophagus. It is increasing in prevalence and incidence in countries like Canada, and frequently occurs in children with other allergic conditions. Unexplained feeding difficulties, vomiting, and solid-food dysphagia, especially in boys with atopy, supports the possibility of having EoE. A formal diagnosis is obtained by reviewing esophageal biopsies obtained through upper endoscopy performed while the patient is taking a proton pump inhibitor. Once EoE has been established, management should involve working collaboratively with gastroenterology and allergy specialists. Medical or dietary treatments are acceptable therapeutic approaches.


问:在我的诊所里,一个患有花生过敏和哮喘的13岁男孩在吞咽固体物质有困难的几年之后,最近被诊断为嗜酸性粒细胞性食管炎(EoE)。什么是EoE,如何诊断和管理?

答:嗜酸性粒细胞性食管炎是一种引起食管炎症的免疫介导性疾病。在加拿大等国家,它的患病率和发病率都在增加,并且经常发生在患有其他过敏疾病的儿童身上。不明原因的进食困难、呕吐和固体食物吞咽困难,特别是在特应性男孩中,支持EoE的可能性。正式诊断是在患者服用质子泵抑制剂时,通过上内窥镜检查获得的食管活检。一旦确定EoE,管理应包括与胃肠病学和过敏专家合作。药物或饮食治疗是可接受的治疗方法。


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ESPGHAN:儿童嗜酸性粒细胞性食管炎的诊断和管理指南(2024更新版)
发布时间:  2024年8月6日
制定者:  
欧洲儿科胃肠病学、肝病学和营养协会(ESPGHAN,European Society for Paediatric Gastroenterology

88人浏览

0收藏

0次下载

摘要

Question: After a few years of difficulty swallowing solids and feeling like food was getting stuck, a 13-year-old boy in my practice with peanut allergy and asthma was recently diagnosed with eosinophilic esophagitis (EoE). What is EoE and how is it diagnosed and managed?

Answer: Eosinophilic esophagitis is an immune-mediated disease resulting in inflammation of the esophagus. It is increasing in prevalence and incidence in countries like Canada, and frequently occurs in children with other allergic conditions. Unexplained feeding difficulties, vomiting, and solid-food dysphagia, especially in boys with atopy, supports the possibility of having EoE. A formal diagnosis is obtained by reviewing esophageal biopsies obtained through upper endoscopy performed while the patient is taking a proton pump inhibitor. Once EoE has been established, management should involve working collaboratively with gastroenterology and allergy specialists. Medical or dietary treatments are acceptable therapeutic approaches.


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