IgA nephropathy and IgA vasculitis with nephritis, albeit rare, represent two relatively frequent glomerular conditions in childhood. Compared to adults, pediatric IgA nephropathy has a more acute presentation, most frequently with synpharyngitic macrohematuria and histologically with more intense inflammation and less intense chronic damage. Management of these conditions is controversial and supported by little high-quality evidence. The paucity of evidence is due to the disease heterogeneity, its inter-ethnic variability, and the difficulty of extrapolating data from adult studies due to the peculiarities of the condition in children. IgA vasculitis with nephritis is a kidney manifestation of a systemic disorder, typical of the pediatric age, in which both the diagnosis of kidney involvement and its management are poorly defined, and an interdisciplinary approach is crucial. Both conditions can have a profound and long-lasting impact on kidney function and the global health of affected children. The International Pediatric Nephrology Association has therefore convened a diverse international group of experts from different disciplines to provide guidance on the recommended management of these conditions in children and to establish common definitions and define priorities for future high-quality, evidence-based collaborative studies for the benefit of children.

IgA肾病和IgA血管炎伴肾炎，虽然罕见，但在儿童时期是两种相对常见的肾小球疾病。与成人相比，儿童IgA肾病具有更急性的表现，最常见的是咽喉性大血尿，组织学上有更强烈的炎症和较轻的慢性损伤。这些疾病的管理是有争议的，并且几乎没有高质量的证据支持。证据的缺乏是由于疾病的异质性，其种族间的可变性，以及由于儿童疾病的特殊性，从成人研究中推断数据的困难。IgA血管炎合并肾炎是一种全身性疾病的肾脏表现，典型的儿童年龄，其中肾脏受累的诊断和治疗都不明确，跨学科的方法是至关重要的。这两种情况都可能对受影响儿童的肾功能和全球健康产生深远而持久的影响。因此，国际儿童肾脏病协会召集了来自不同学科的国际专家小组，为儿童这些疾病的推荐管理提供指导，并为未来高质量的、基于证据的合作研究确定共同的定义和优先事项，以造福儿童。