This WHO Clinical practice guideline for influenza is an update and expansion from the previously published WHO guideline on the clinical management of patients with severe influenza or at risk of severe influenza.

These updated guidelines provide recommendations on the management of both severe and non-severe influenza and also includes recommendations on the use of antiviral medications to prevent influenza virus infection in individuals exposed to the virus in the previous 48 hours. This update applies to patients with seasonal influenza viruses, pandemic influenza viruses and novel influenza A viruses known to cause severe illness in infected humans.

This update also includes baseline risk estimates for hospitalization and death and proposed definitions of patients at high or extremely high risk of developing severe influenza, so as to enable the recommendations to be targeted appropriately.

这份世卫组织流感临床实践指南是对之前发布的世卫组织关于重症流感患者或有重症流感风险的患者的临床管理指南的更新和扩展。

这些更新版指南提供了有关重症和非重症流感管理的建议，还包括有关使用抗病毒药物预防在过去48小时内接触过流感病毒的人感染流感病毒的建议。本更新适用于季节性流感病毒、大流行性流感病毒和已知可导致受感染人类重症的新型甲型流感病毒的患者。

本次更新还包括住院和死亡的基线风险估计值，以及高危或极高危重症流感患者的拟议定义，以便使建议具有适当的针对性。