Purpose: Pituitary surgery is the mainstay treatment for most pituitary adenomas, but many questions remain about perioperative and long-term management and outcomes. This study aimed to identify the most pressing research priorities in pituitary surgery with input from patients, caregivers, and healthcare professionals.

Methods: An initial survey of patients, caregivers, and healthcare professionals assembled priorities related to preoperative care, surgical techniques, and postoperative management in pituitary surgery. Priorities were thematically grouped into summary priorities, and those answered by existing evidence were omitted following a literature review. An interim survey asked patients, caregivers, and healthcare professionals to select their top 10 priorities from the remaining list. The highest-ranked priorities advanced to a consensus meeting, where the top 10 questions were prioritized.

Results: In the initial survey, 147 participants-60.5% of whom were patients, caregivers, or patient support group representatives-submitted 785 priorities, which were then condensed into 52 summary priorities. After a literature review, 33 unanswered priorities were included in the interim survey, completed by 155 respondents, of whom 54.2% were patients, caregivers, or patient support group representatives. The top-ranked priorities were discussed by 14 participants (7 patients and 7 healthcare professionals) during a consensus meeting. The top 10 priorities covered a variety of themes including enhancing diagnosis and management of pituitary adenomas, advancing surgical techniques and technologies, optimizing the prediction of outcomes and complications, and improving patient support and follow-up.

Conclusions: The top 10 research priorities in pituitary surgery aim to align researchers and direct funding in order to maximize impact and champion patient representation.

目的：垂体手术是大多数垂体腺瘤的主要治疗方法，但关于围手术期和长期管理和结果仍有许多问题。本研究旨在根据患者、护理人员和医疗保健专业人员的意见，确定垂体手术中最紧迫的研究重点。

方法：对患者、护理人员和卫生保健专业人员进行初步调查，收集与垂体手术术前护理、手术技术和术后管理相关的优先事项。优先事项按主题分组为摘要优先事项，并在文献回顾后省略了现有证据的回答。一项中期调查要求患者、护理人员和医疗保健专业人员从剩下的清单中选出他们最优先考虑的10项。排名最高的问题进入了协商一致的会议，在会议上，最重要的10个问题被优先考虑。

结果：在最初的调查中，147名参与者（其中60.5%是患者、护理人员或患者支持小组代表）提交了785个优先事项，然后将其浓缩为52个摘要优先事项。经过文献回顾，在中期调查中纳入了33个未回答的优先事项，由155名受访者完成，其中54.2%是患者、护理人员或患者支持小组代表。在一次共识会议上，14名参与者（7名患者和7名医疗保健专业人员）讨论了排名最高的优先事项。十大优先事项涵盖了多种主题，包括加强垂体腺瘤的诊断和管理，推进手术技术和技术，优化预后和并发症的预测，以及改善患者支持和随访。

结论：垂体外科的十大研究重点旨在调整研究人员和直接资助，以最大限度地影响和支持患者代表。