Irritable bowel syndrome (IBS) is a chronic, disabling, and functional bowel disorder that significantly affects social functioning and reduces quality of life and increases social costs. The Korean Society of Neurogastroenterology and Motility published clinical practice guidelines on the management of IBS based on a systematic review of the literature in 2017, and planned to revise these guidelines in light of new evidence on the pathophysiology, diagnosis, and management of IBS. The current revised version of the guidelines is consistent with the previous version and targets adults diagnosed with or suspected of having IBS. These guidelines were developed using a combination of de novo and adaptation methods, with analyses of existing guidelines and discussions within the committee, leading to the identification of key clinical questions. Finally, the guidelines consisted of 22 recommendations, including 3 concerning the definition and risk factors of IBS, 4 regarding diagnostic modalities and strategies, 2 regarding general management, and 13 regarding medical treatment. For each statement, the advantages, disadvantages, and precautions were thoroughly detailed. The modified Delphi method was used to achieve expert consensus to adopt the core recommendations of the guidelines. These guidelines serve as a reference for clinicians (including primary care physicians, general healthcare providers, medical students, residents, and other healthcare professionals) and patients, helping them to make informed decisions regarding IBS management.

肠易激综合征（IBS）是一种慢性、致残性、功能性肠道疾病，严重影响社会功能，降低生活质量，增加社会成本。韩国神经胃肠病学与运动学会于 2017 年根据文献的系统性回顾发布了肠易激综合征管理的临床实践指南，并计划根据肠易激综合征的病理生理学、诊断和管理方面的新证据对这些指南进行修订。目前的指南修订版与上一版保持一致，主要针对确诊或疑似患有肠易激综合征的成年人。该指南的制定结合了新方法和适应性方法，对现有指南进行了分析，并在委员会内部进行了讨论，最终确定了关键的临床问题。最后，指南包括 22 项建议，其中 3 项涉及肠易激综合征的定义和风险因素，4 项涉及诊断方法和策略，2 项涉及一般管理，13 项涉及药物治疗。对每项建议的优缺点和注意事项都进行了详细说明。通过改良德尔菲法，专家们达成共识，采纳了指南的核心建议。这些指南可作为临床医生（包括初级保健医生、普通医护人员、医科学生、住院医师和其他医护人员）和患者的参考，帮助他们就肠易激综合征的治疗做出明智的决定。