Autoimmune hepatitis (AIH) is a chronic liver disease of unknown aetiology which may affect any patient irrespective of age, sex, and ethnicity. At baseline, the clinical spectrum of the disease varies largely from asymptomatic cases to acute liver failure with massive hepatocyte necrosis. The aim of these EASL guidelines is to provide updated guidance on the diagnosis and management of AIH both in adults and children. Updated guidance on the management of patients with variants and specific forms of AIH is also provided, as is detailed guidance on the management of AIH-associated cirrhosis, including surveillance for portal hypertension and hepatocellular carcinoma, as well as liver transplantation in decompensated cirrhosis.

自身免疫性肝炎（AIH）是一种病因不明的慢性肝病，可影响任何年龄、性别和种族的患者。从无症状到伴有大量肝细胞坏死的急性肝功能衰竭，该病的临床表现各不相同。这些EASL指南旨在为成人和儿童AIH的诊断和治疗提供最新指导。此外，还提供了关于变异型和特殊形式AIH患者管理的最新指南，以及关于AIH相关性肝硬化管理的详细指南，包括门静脉高压和肝细胞癌的监测，以及失代偿期肝硬化的肝移植。