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成人炎症性肠病:BSG指南(2025)

制定者:
英国胃肠病学会(BSG,British Society of Gastroenterology)

2025年6月22日

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摘要:

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In response to recent advancements in inflammatory bowel disease (IBD) management, the British Society of Gastroenterology (BSG) Clinical Services and Standards Committee (CSSC) has commissioned the BSG IBD section to update its guidelines, last revised in 2019. These updated guidelines aim to complement the IBD standards and promote the use of the national primary care diagnostic pathway for lower gastrointestinal symptoms to enhance diagnostic accuracy and timeliness. Formulated through a systematic and transparent process, this document reflects a consensus of best practices based on current evidence. The guideline, while developed primarily for the UK, is structured to support IBD management internationally. It is endorsed by the BSG executive board and CSSC without external commercial funding, with involvement primarily supported through professional roles in public institutions and the National Health Service (NHS). Methodological revisions since the prior guidelines have enhanced rigor in technical review and development, with methodology details published independently following peer review. In developing the recommendations, 89 clinical experts and stakeholders participated in an online survey, identifying primary outcomes, such as clinical and endoscopic remission, as well as adverse event metrics, all stratified by clinically relevant effect sizes. These guidelines are intended to support clinical decision- making but are not prescriptive, recognizing that individual clinical scenarios may warrant tailored approaches. Further research may inform future revisions as new evidence emerges.

针对炎症性肠病(IBD)管理领域的最新进展,英国胃肠病学会(BSG)临床服务与标准委员会(CSSC)委托学会IBD分部更新2019年修订的指南。本次更新旨在完善IBD诊疗标准,推动全国基层医疗机构针对下消化道症状的诊断路径应用,从而提升诊断准确性与时效性。该指南通过系统化、透明化的流程制定,凝聚了基于当前循证医学证据的最佳实践共识。

虽然主要面向英国医疗体系设计,但指南结构兼顾国际IBD管理需求。文件获得BSG执行委员会及CSSC认证,无外部商业资助,主要参与人员均来自公共机构及英国国家医疗服务体系(NHS)的专业岗位。相较既往版本,本次修订强化了技术评审与开发流程的严谨性,方法论细节经同行评议后另行发表。

在制定推荐意见过程中,89位临床专家及利益相关者通过在线调研确定核心结局指标——包括临床缓解与内镜缓解等疗效指标及不良事件指标,所有指标均按临床相关效应量分层。本指南旨在辅助临床决策而非硬性规定,强调需根据个体化临床情境采取针对性诊疗方案。随着新证据的出现,未来将通过深入研究推动指南持续更新。


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临床指南
成人炎症性肠病:BSG指南(2025)
发布时间:  2025年6月22日
制定者:  
英国胃肠病学会(BSG,British Society of Gastroenterology)

693人浏览

0收藏

2次下载

摘要

In response to recent advancements in inflammatory bowel disease (IBD) management, the British Society of Gastroenterology (BSG) Clinical Services and Standards Committee (CSSC) has commissioned the BSG IBD section to update its guidelines, last revised in 2019. These updated guidelines aim to complement the IBD standards and promote the use of the national primary care diagnostic pathway for lower gastrointestinal symptoms to enhance diagnostic accuracy and timeliness. Formulated through a systematic and transparent process, this document reflects a consensus of best practices based on current evidence. The guideline, while developed primarily for the UK, is structured to support IBD management internationally. It is endorsed by the BSG executive board and CSSC without external commercial funding, with involvement primarily supported through professional roles in public institutions and the National Health Service (NHS). Methodological revisions since the prior guidelines have enhanced rigor in technical review and development, with methodology details published independently following peer review. In developing the recommendations, 89 clinical experts and stakeholders participated in an online survey, identifying primary outcomes, such as clinical and endoscopic remission, as well as adverse event metrics, all stratified by clinically relevant effect sizes. These guidelines are intended to support clinical decision- making but are not prescriptive, recognizing that individual clinical scenarios may warrant tailored approaches. Further research may inform future revisions as new evidence emerges.

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