Objectives. Effective treatment of laryngeal cancer requires clinical decision-making that balances survival outcomes with the preservation of essential functions, such as voice and swallowing. This study, led by the Clinical Practice Guideline Committee of the Korean Society of Head and Neck Surgery, aims to establish evidence-based recommendations to guide surgeons in optimizing treatment decisions for patients with laryngeal cancer. 

Methods. A literature search was performed in the PubMed, Embase, Cochrane Library, and KoreaMed databases by a literature search expert and subsequently reviewed by a panel of 39 committee experts. The Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) method was employed to assess the quality of evidence and develop and report the recommendations. The strength of each recommendation reflects the guideline panel’s confidence that the benefits of an intervention outweigh its risks for the target population. After drafting the guidelines, Delphi questionnaires were distributed to members of the Korean Society of Head and Neck Surgery and an external reviewer panel. 

Results. In total, 15 evidence-based recommendations are provided, addressing six critical aspects of laryngeal cancer treatment: early-stage treatment, treatment of locally advanced cancer, neck management, adjuvant therapy, swallowing rehabilitation, and salvage treatment for recurrent tumors. 

Conclusion. The guidelines provide evidence-based, validated recommendations to support clinicians in making optimal treatment decisions for laryngeal cancer.

目标：喉癌的有效治疗需要临床决策在生存结局与保留发声、吞咽等重要功能之间取得平衡。本研究由韩国头颈外科学会临床实践指南委员会主导，旨在制定循证推荐意见，为外科医生优化喉癌患者的治疗决策提供指导。  

方法：由文献检索专家在PubMed、Embase、Cochrane Library及KoreaMed数据库中进行文献检索，随后由39名委员会专家组成的小组对文献进行审核。采用推荐分级、评估、制定与评价（GRADE）方法评估证据质量，并据此制定和报告推荐意见。每项推荐的强度反映了指南小组对该干预措施针对目标人群的获益大于风险这一结论的信心。指南草案完成后，向韩国头颈外科学会成员及外部评审小组发放德尔菲问卷（以收集反馈）。

结果：共提出15项循证推荐意见，涉及喉癌治疗的六个关键方面：早期喉癌的治疗、局部晚期喉癌的治疗、颈部管理、辅助治疗、吞咽康复及复发性肿瘤的挽救治疗。

结论：本指南提供了循证且经验证的推荐意见，以支持临床医生为喉癌患者做出最佳治疗决策。