Executive summary

The consolidated WHO Guidelines for malaria present all of the current WHO recommendations for malaria. These are the product of careful evaluation following standardized methods as part of the WHO process for developing guidelines The recommendations for malaria vaccines have been developed following the procedures of the WHO Strategic Advisory Group of Experts on Immunization (SAGE). WHO uses strictly defined processes to assess the quality, consistency and completeness of evidence to determine the strength of each recommendation.

WHO malaria recommendations are intended to be short, evidence-based, actionable statements. They are usually accompanied by supplementary remarks drawing attention to contextual and implementation considerations that may influence the appropriateness and impact of a recommendation in different settings. Clearly distinguishing recommendations from their associated contextual considerations provides information national policy-makers to consider when adopting and adapting the recommended strategies that are most appropriate in their settings.

This online platform and the associated PDF help to distinguish the formal recommendations from the supplementary statements. The Global Malaria Programme will use this platform to produce “living guidelines”, which can be updated more rapidly than printed documents as new evidence becomes available. The tabs below each recommendation enable users to access the research evidence and evidenceto-decision (EtD) frameworks that informed the recommendation. There is also a feedback tab where users are encouraged to provide input directly related to each intervention.

执行摘要

世卫组织综合疟疾指南呈现了世卫组织当前所有关于疟疾的建议。这些建议是遵循标准化方法进行仔细评估的成果，也是世卫组织指南制定流程的一部分。关于疟疾疫苗的建议是按照世卫组织免疫战略咨询专家组（SAGE）的程序制定的。世卫组织采用严格界定的流程评估证据的质量、一致性和完整性，以确定每项建议的强度。

世卫组织的疟疾建议旨在成为简短、循证且可操作的表述。这些建议通常附有补充说明，提醒注意背景和实施方面的考量——这些考量可能会影响建议在不同环境中的适用性和效果。明确区分建议与其相关的背景考量，可为国家决策者在采纳和调整最适合其所在环境的建议策略时提供参考信息。

本在线平台及相关PDF文件有助于区分正式建议与补充说明。全球疟疾规划将利用该平台制作“动态指南”，随着新证据的出现，这类指南可比印刷文件更新得更快。每项建议下方的标签页使用户能够获取为该建议提供依据的研究证据和证据到决策（EtD）框架。此外还有一个反馈标签页，鼓励用户提供与每项干预措施直接相关的意见。