中文
EN

真菌性眼内炎的诊断与管理国际共识与指南(2025)

制定者:
亚太玻璃体视网膜协会

2025年10月12日

117人浏览

0收藏

1次下载

摘要:

中英对照

Fungal endophthalmitis represents one of the most challenging intraocular infections to diagnose and manage in ophthalmology. Despite advances in diagnostic techniques and treatment options, numerous controversies persist regarding optimal approaches to this sight-threatening condition. 


Due to the low incidence and signifcant variation in the severity and time of presentations, no large-scale randomized controlled trials have been done. Therefore, identify‑ ing controversies and deliberating the best approach to diagnosing and treating fungal endophthalmitis by international experts would help establish consensus statements that can guide clinical practice. 


The Asia-Pacifc Academy of Professors in Ophthalmology (AAPPO), Asia-Pacifc Vitreo-Retina Society (APVRS), and Asia-Pacifc Society of Ocular Infammation and Infection (APSOII) saw this critical gap and formed an international panel of experts comprising 24 experts to establish 20 consensus statements. 


While there is consensus on the need for early diagnosis and prompt administration of antifun‑ gal therapy, there are conficting views on the optimal diagnostic approach to be taken, the role and timing of performing vitrectomy, and the use of systemic antifungal agents. 


A particularly contested topic is the role of corticosteroids. In estab‑ lishing the 20 consensus statements, these thus serve as guidelines for diagnosing and managing fungal endophthalmitis.

真菌性眼内炎是眼科领域中最具诊断和治疗挑战性的眼内感染之一。尽管诊断技术和治疗方案不断进步,针对这一威胁视力疾病的优化诊疗方案仍存在诸多争议。


由于该疾病发病率低、临床表现的严重程度和发病时间存在显著差异,目前尚未开展大规模随机对照试验。因此,通过国际专家识别争议点并探讨真菌性眼内炎的最佳诊疗策略,将有助于建立指导临床实践的共识声明。


亚太眼科教授学会(AAPPO)、亚太玻璃体视网膜学会(APVRS)及亚太眼炎症与感染学会(APSOII)注意到这一关键空白,组建了由24名专家构成的国际专家组,共同制定了20条共识声明。


尽管专家们一致认为需要早期诊断并及时给予抗真菌治疗,但在最佳诊断方案选择、玻璃体切除术的作用与时机、以及全身抗真菌药物的应用等方面仍存在分歧。


其中,关于皮质类固醇使用方案的争议尤为显著。最终确立的20条共识声明,为真菌性眼内炎的诊断与管理提供了临床指导规范。


下载医学界医生站


关注医生站公众号
临床指南
真菌性眼内炎的诊断与管理国际共识与指南(2025)
发布时间:  2025年10月12日
制定者:  
亚太玻璃体视网膜协会

117人浏览

0收藏

1次下载

摘要

Fungal endophthalmitis represents one of the most challenging intraocular infections to diagnose and manage in ophthalmology. Despite advances in diagnostic techniques and treatment options, numerous controversies persist regarding optimal approaches to this sight-threatening condition. 


Due to the low incidence and signifcant variation in the severity and time of presentations, no large-scale randomized controlled trials have been done. Therefore, identify‑ ing controversies and deliberating the best approach to diagnosing and treating fungal endophthalmitis by international experts would help establish consensus statements that can guide clinical practice. 


The Asia-Pacifc Academy of Professors in Ophthalmology (AAPPO), Asia-Pacifc Vitreo-Retina Society (APVRS), and Asia-Pacifc Society of Ocular Infammation and Infection (APSOII) saw this critical gap and formed an international panel of experts comprising 24 experts to establish 20 consensus statements. 


While there is consensus on the need for early diagnosis and prompt administration of antifun‑ gal therapy, there are conficting views on the optimal diagnostic approach to be taken, the role and timing of performing vitrectomy, and the use of systemic antifungal agents. 


A particularly contested topic is the role of corticosteroids. In estab‑ lishing the 20 consensus statements, these thus serve as guidelines for diagnosing and managing fungal endophthalmitis.

收藏
切换中文
阅读全文